Rare form of chronic pyelonephritis and represents a chronic granulomatous disease resulting in a non-functioning kidney
Aetiology
- Chronic granulomatous process believed to be the result of subacute/chronic infection inciting a chronic but incomplete immune reaction
Pathophysiology
- Inflammatory but has all radiological features of malignancy
Clinical presentation
- Typically vague, consisting of constitutional symptoms such as malaise, weight loss and low-grade fever
- Haematuria and flank pain are sometimes encountered
Investigations
- Imaging - x-ray, USS, CT (most useful), MRI
Management
- Surgical nephrectomy is usually curative