Brain Metastases

Aetiology

  • Any cancer can metastasize to the brain but the most common tumours to do so are those arising from:
    • Lung
    • Breast
    • Skin (melanoma)
    • Kidney

Management

  • Cerebral oedema surrounding the tumours responds to steroid therapy
  • Many systemic therapies for the primary tumour do not cross the blood–brain barrier and therefore do not control brain metastases
  • Management options include resection via neurosurgery, stereotactic radiotherapy and whole-brain radiotherapy