Arthritic Joint Treatment

Basic principles

  1. Rest/analgesia/activity modification
  1. Some joints may benefit from splinting e.g. rheumatoid hands, thumb CMC OA
  1. Steriod injections may provide temporary relief
  1. Surgery - fusion, replacement, excision

Arthroplasty

  • Involves either replacement of part of the joint (hemiarthroplasty) or the whole joint (total joint replacement)

Choice of materials

  • Joint replacements can be made of stainless steel, cobalt chrome, titanium alloy, polyethylene and ceramic
  • Components may or may not be cemented (bone cement - PMMA) - advantages and disadvantages of both
  • The surfaces can consist of a metal‐polyethylene, ceramic‐polyethylene, ceramic–ceramic or metal‐metal bearing couple
  • There is no single ideal material or combination of materials for a joint replacement
  • Ultimately the joint replacement will fail due to loosening (caused by wear particles producing an inflammatory response or high stresses) or breakage of the joint replacement components
  • Metal particles can cause an inflammatory granuloma (known as a pseudotumour) which can cause muscle and bone necrosis
  • Polyethylene particles can cause an inflammatory response in bone with subsequent bone resorption (osteolysis) resulting in loosening
  • Ceramics can shatter with fatigue due to their brittleness

Indications for a Total Knee Replacement

  • Only for older, medically fit appropriate patient with end stage arthritis and severe pain refractory to chronic management
    • Constant severe pain, sleep disturbance, pain limiting function/walking distance, frequent bad 'flare-ups'
    • Those with milder OA and severe pain tend not to do well - increased chance of developing chronic pain
  • Older patient where replacement will last for good - 60+ as a guide
    • Expect TKR to last 15-20 years in older, low demand patients if put in well

Indications for a Total Hip Replacement

  • Pain
  • 90% of cases wil be pain free after recovery
  • Vast majority of cases will have large functional improvement
  • In a low demand older patient the estimated lifespan of a THA is around 15 years

Complications

  • Early local complications: infection, dislocation, instability, leg length discrepancy, nerve injury, arterial bleeding/ischaemia, bleeding, DVT
  • Early general complications: hypovolaemia, shock, acute renal failure, MI, ARDS, PE, chest infection, urine infection
  • Late local complications: infection (haematogenous spread), loosening, fracture, implant breakage, pseudotumour formation

Revision joint replacements

  • Revision joint replacements are a bigger procedure than the primary procedure with often substancial blood loss, increased the complication rates and often poorer functional outcome
  • Revision joint replacements tend not to last as long as primary joint replacement
  • Once a revision fails - risk of fusion or amputation

Other considerations

  • Younger patients more likely to need revision surgery due to having increased demands on the replacement, and 'outliving' their replacement
  • 20% of patients who have a TKR have unexplained moderate-severe pain
    • May be due to the complexity of and reliance upon the tension of the soft tissues around the knee
    • Predictors - young, obesity, psychological distress, preexisting chronic pain, less severe OA

Alternatives to a total knee replacement

Unicompartmental knee replacement

  • Only the worn area of the knee is replaced
  • Less invasive, no ligaments removed or lengthened
  • Knee may feel more natural
  • Fairly easy to revise
  • Many cases not suitable
  • Reoperation rate significantly higher than TKR
  • Major concern is progression of OA in unreplaced knee - might regret not doing TKR

Osteotomy

  • Surgical realignment of a bone which can be used for deformity correction or to redistribute load across an arthritic joint and shift load onto an undiseased part
  • Can be used for early arthritis in the knee and hip
  • Doesn't remove the damaged joint, controversial
  • Only for very active patients who would damage or loosen a joint replacement

Cartilage regeneration surgery

  • Cartilage regeneration surgery may be beneficial in a case of small localised area of articular cartilage damage with persistent pain
  • Results unpredictable
  • Does not work for more general/widespread changes of OA or multiple defects

Keyhole surgery - 'clean out'

  • Performed histortically to try to alleviate symptoms and prevent knee replacement
  • Usually ineffective, any benefit tends to be short lived
  • Should not be offered on NHS

Surgical joint options for smaller joints

Excision or resetion arthroplasty

  • Involves the removal of bone and cartilage of one or both sides of the joint
  • Quite disabling for larger joints but can be an effective procedure for smaller joints (e.g. 1st CMC joint in foot for hallux valgus)
  • Occasionally utilized after failure of hip or shoulder replacement

Arthrodesis

  • Surgical stiffening or fusion of a joint in a position of function
  • The remaining hyaline cartilage of the joint and subchondral bone is removed and the joint is stabilized, resulting in bony union and fusion
  • Alleviates pain but function may be limited, particularly in large joints, and may increase pressure in surrounding joints leading to arthritic change
  • Used in end stage ankle arthritis, wrist arthritis and hallux rigidus

Upper limb arthritis surgery

Rheumatoid hand problems

  • Synovectomy
  • Tendon realignemnt
  • Tendon replacement
  • Fusion

Elbow

  • Arthritic change at the radio‐capitellar joint which has failed non-operative management can be treated with surgical excision of the radial head - good pain relief with minimal functional limitation
  • An elbow severely affected by RA or OA at the humero‐ulnar joint which isn't satisfactorily treated with conservative management can be treated surgically with a Total Elbow Replacement - lifting limited to 2.5kg posteriorly following replacement
    • Elbow replacements have a limited life span and so are not good for young/active patients

Shoulder

  • Anatomic replacement
  • Reverse polarity shoulder replacement for OA secondary to rotator cuff tear