Cholangiocarcinoma

Cancer of the bile ducts

Aetiology

  • PSC is a risk factor

Clinical presentation

  • Jaundice
  • Weight loss
  • Anorexia
  • Lethargy

Investigations

LFTs

  • Cholestatic - ALP > ALT/AST, ↑ GGT and bilirubin

Imaging

  • USS
  • MRCP
  • Spiral CT/ERCP/PTC

Management

  • Surgery - bile duct and liver resection
  • Palliative - biliary stent