Acute Colonic Pseudo-Obstruction (Ogilvie’s Syndrome)

Characterized by acute massive colon dilatation involving primarily the right side of the colon and without a mechanical cause

Aetiology

  • Most common in frail/elderly patients
  • Conditions commonly associated with Olgilvie's syndrome include:
    • Recent surgery e.g. hip replacement surgery, CABG
    • Recent trauma e.g. spinal fracture
    • Recent severe illness e.g. pneumonia
    • Electrolyte imbalance or endocrine disorders e.g. hypercalcaemia
    • Medication e.g. opioids
    • Neurological disease e.g. Parkinson’s disease

Pathophysiology

  • Most commonly affects the caecum and ascending colon, however can affect the whole bowel
  • Exact mechanism is unknown; it is thought to be due to an interruption of the autonomic nervous supply to the colon resulting in the absence of smooth muscle action in the bowel wall

Clinical presentation

Symptoms

  • Most patients will present with the clinical features of mechanical bowel obstruction - abdominal pain, abdominal distension, constipation, vomiting

Signs

  • On examination the abdomen will be distended and tympanic

Investigations

  • AXR will show bowel distension
  • Abdominal-pelvis CT scan with IV contrast - will show dilatation of the colon, as well as definitively excluding a mechanical obstruction and assessing for any complications

Management

  • Most cases can be managed conservatively (nil-by-mouth, IV fluids) - with aggressive management the massive colon dilatation can resolve and normal function can return
  • Colonic decompression may be required if distension is causing pain or respiratory compromise