Rare, benign tumour of the CN VIII nerve sheath that arises in internal auditory meatus
Aetiology
- Aetiology unknown but may be associated with extensive exposure to excessively lound noise
- If bilateral and young, consider neurofibromatosis type 2
Pathophysiology
- Associated with vestibular portion of CN VIII
- Occur within temporal bone, represent 80-90% of cerebellopontine angle tumours
- 95% are sporadic and unilateral
- Gross appearance - circumscribed tan/white/yellow mass
- Histology - encapsulated, two growth patterns (Antoni A and Antoni B)
Clinical presentation
- Progressive sensorineural unilateral hearing loss and tinnitus
- Imbalance in larger tumours
- Facial numbness can occur due to compression of the trigeminal nerve as the tumour enlarges
Investigations
Management
- Surgical excision is the definitive management
- Small lesions that are not growing may be monitored (MRI) - initially with a 6 month interval