Dermatophyte fungal infection of the scalp hair follicles and surrounding skin
Aetiology
Caused by dermatophytes, mainly:
- Trichophyton tonsurans (most common worldwide)
- Trichophyton violaceum
- Microsporum canis
- Microsporum audouinii
Patterns of Hair Invasion
- Endothrix: fungal spores inside hair shaft (Trichophyton)
- Ectothrix: spores on hair surface (Microsporum)
Epidemiology
- Most common in children aged 3–7 years
- Rare after puberty (protective effect of sebum)
- Higher prevalence in crowded living conditions, bad hygiene, and immunocompromised individuals.
Pathophysiology
- Dermatophytes invade the stratum corneum of the scalp.
- The fungus penetrates the hair shaft.
- Hair becomes fragile and breaks at or near the scalp surface.
- Inflammatory response varies depending on organism and host immunity.
Clinical presentation
Non-inflammatory Tinea Capitis
- Scalp scaling
- Patchy alopecia
- Broken hairs (“black dot” appearance)
- Minimal erythema or pruritus


Inflammatory Tinea Capitis
- Kerion: painful, boggy inflammatory mass
- Pustules, crusting
- Tender cervical lymphadenopathy
- Risk of scarring alopecia

Favus (severe form)
- Yellow crusts (scutula)
- Mousy odor
- Permanent scarring

Investigations
- KOH 10% Examination
- Shows characteristic fungal true hyphae and arthrospores
- Wood’s Lamp
- Green fluorescence (mainly Microsporum species)
- Trichophyton species usually do not fluoresce
- Fungal Culture
- Gold standard for species identification
- Takes 2–4 weeks
Management
⚠️ Topical therapy alone is ineffective because the fungus infects hair follicles.
Grey Patch — Microsporum
First-line options
- Griseofulvin
- 20–25 mg/kgBB/day for 8 weeks
- Drug of choice in children
Alternatives
- Terbinafine
- Weight-based dosing for 4–6 weeks
- 10-20 kg → 62.5 mg/day
- 20-40 kg → 125 mg/day
- >40 kg → 250 mg/day
- More effective against Trichophyton
- Itraconazole 50-100 mg/day for 6 weeks
Topical — Adjuvants
- Selenium sulfide 1% and 2.5% shampoo 2-4x/week
- Ketoconazole 2% shampoo 2x/day for 2-4 weeks
Black Dot — Trichophyton
- Terbinafine (first line)
- Weight-based dosing for 2–4 weeks
- 10-20 kg → 62.5 mg/day
- 20-40 kg → 125 mg/day
- >40 kg → 250 mg/day
- Griseofulvin 20–25 mg/kg/day for 8 weeks
- Itraconazole 50-100 mg/day for 2 weeks
- Fluconazole 6 mg/kg/day for 3-4 weeks